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KMID : 0360220080490061033
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 6 p.1033 ~ p.1040
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Two Cases of Topiramate-induced Acute Myopia
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Kim Seong-Wook
Seo Seong-Gwan
Her Jun
Ahn Ki-Soo
Choi Bong-Joon
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Abstract
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Purpose:We describe 2 cases of bilateral acute myopia associated with topiramate, a drug that has recently been prescribed for epilepsy or weight reduction.
Case summary:A 24-year-old woman and a 25-year-old woman, both previously devoid of ocular problems, visited our hospital with blurry vision after taking topiramate for weight reduction. A thorough medical history review and ocular examinations, including a slit lamp examination, were performed.
Conclusions: Slit-lamp examinations revealed forward displacement of the lens-iris diaphragm, which resulted in myopia and anterior chamber shallowing. Discontinuation of topiramate and the administration of cycloplegic agents successfully resolved the symptoms.
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KEYWORD
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Acute myopia, Cycloplegic agent, Topiramate
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